Monosodium glutamate-induced oxidative kidney damage and possible mechanisms: a mini-review
نویسندگان
چکیده
منابع مشابه
Kidney and Liver Functions and Stress Oxidative Markers of Monosodium Glutamate-Induced Obese Rats
The purpose of the present study was to determine the function and oxidative status in kidney and liver using a model of obesity induced by neonatal treatment of rats with monosodium glutamate, and to investigate the association of these metabolic changes with antioxidant enzymes, oxidative stress and NO generation. Methods: neonate male Wistar rats were subcutaneously injected, with monosodium...
متن کاملThe effect of coenzyme Q10 on oxidative stress parameters and testicular tissue damage in rats following monosodium glutamate induced excitatory intoxication
Background: Monosodium glutamate (MSG) is known as a food flavor enhancer that can adversely affect the male reproductive system. The present study was investigated the protective effect of coenzyme Q10 (Co-Q10) against MSG-induced oxidative stress and histopathological changes in rat testicular tissue. Materials and methods: In this experimental study, 40 adult male Wistar rats were randomly ...
متن کاملNatural products as safeguards against monosodium glutamate-induced toxicity
Monosodium glutamate is a sodium salt of a nonessential amino acid, L-glutamic acid, which is widely used in food industry. Glutamate plays an important role in principal brain functions including formation and stabilization of synapses, memory, cognition, learning, as well as cellular metabolism. However, ingestion of foodstuffs rich in monosodium glutamate can result in the outbreak of severa...
متن کاملHomocysteine-induced oxidative damage: mechanisms and possible roles in neurodegenerative and atherogenic processes.
Increased blood plasma concentrations of the sulphur amino acid homocysteine ("homocysteinemia") have been brought into context with neurodegenerative and arteriosclerotic symptoms and diseases. We recently reported on biochemical model reactions on the prooxidative activity of homocysteine including the desactivation of Na+/K(+)-ATPases and hemolysis of erythrocytes (Preibisch et al., 1993). I...
متن کاملEffect of vitamin E on monosodium glutamate induced hepatotoxicity and oxidative stress in rats.
Monosodium glutamate (MSG), administered to rats (by gavage) at a dose of 0.6 mg/g body weight for 10 days, significantly (P<0.05) induced lipid peroxidation (LPO), decreased reduced glutathione (GSH) level and increased the activities of glutathione-s-transferase (GST), catalase and superoxide dismutase (SOD) in the liver of the animals; these were observed 24 hr after 10 days of administratio...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biomedical Science
سال: 2015
ISSN: 1423-0127
DOI: 10.1186/s12929-015-0192-5